10 Common Medications That Cause Weight Gain

10 Common Medications That Cause Weight Gain

Do you have a hard time losing weight, no matter what you do? You may be surprised to learn that your medications could be the culprit. Many common drugs have been linked to weight gain, including antidepressants, diabetes medications, and birth control pills. In this blog post, we will discuss 10 of the most common medications that can cause weight gain. We will also provide tips for how to counteract the effects of these drugs.

Can Medication Cause You Weight Gain?

Can Medication Cause You Weight Gain?Yes, medication can cause you to gain weight. Certain medications, such as steroids and some antidepressants, are known to increase appetite and lead to weight gain. The reason for this is that these medications change the way your body processes and absorbs food. For example, steroids can cause your body to store more fat and make you feel hungrier.

Additionally, some medications may slow down your metabolism, making it easier for your body to store extra calories as fat. It’s important to talk to your doctor about any potential side effects of medication that could lead to weight gain. Your doctor should be able to provide advice on how to manage any side effects and may be able to suggest an alternative medication.

It’s also important to note that there are other factors that can lead to weight gains, such as poor nutrition and lack of physical activity. Even if your medication is causing you to gain weight, it’s still important to make sure you’re eating a healthy, balanced diet and getting enough exercise. This can help you maintain your weight or even lose weight if necessary.

Finally, it’s important to remember that everyone is different and may respond differently to the same medication. If you’re concerned about gaining weight from a particular medication, talk to your doctor about other possible options.

What Medications Cause Weight Gain?

Medication weight gain may be caused by a variety of different drugs, here are the top 10 common medications that can lead to weight gain:


Certain antidepressant medications, including tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs), have been linked with weight gain. As this class of medications is often used to treat mental health conditions, it can be difficult to stop taking them even if weight gain is an issue.

Diabetes drugs

Insulin is a commonly used diabetes medication that can cause you to gain weight. Additionally, other diabetes medications, such as sulfonylureas and thiazolidinediones (TZDs), can also lead to weight gain. This is because these drugs can increase your appetite and make it more difficult for your body to break down fat.


Corticosteroid medications, including prednisone and hydrocortisone, are commonly prescribed for allergies, asthma, arthritis, and other inflammatory conditions. These medications can cause weight gain due to their anti-inflammatory effects. It works by increasing the amount of fat stored in your body, which can lead to weight gain.


Medications used to treat high blood pressure, such as beta blockers and diuretics, may also lead to weight gain. For example, thiazide diuretics can cause sodium and water retention, which can lead to increased body weight.

Hormone therapy

Hormone replacement therapy (HRT) drugs, including estrogen and progesterone, may cause weight gain due to their effects on metabolism and appetite. Though this is a common side effect of HRT, it can be managed by making lifestyle changes such as exercising more and eating healthily.


Drugs used to treat schizophrenia and bipolar disorder, such as antipsychotics, can lead to significant weight gain in some individuals. There are several types of antipsychotics, and each one can have different effects on weight. For example, the most commonly prescribed antipsychotics, atypical antipsychotics, are associated with more weight gain than traditional ones.

Birth control pills

Birth control pillsIt might come as a surprise, but birth control pills can cause weight gain in some people. The hormones found in these medications may increase appetite and lead to fluid retention, which can add to your body weight. In fact, some studies show that hormonal contraception may cause more weight gain than other types of birth control.

Anti-seizure medications

Drugs used to treat epilepsy and other seizure disorders, such as carbamazepine and valproate, may also lead to weight gain. Because this type of medication can affect the way your body metabolizes sugar and fat, it can lead to an increase in body weight.


Medications used to treat HIV/AIDS, such as protease inhibitors and non-nucleoside reverse transcriptase inhibitors, can cause weight gain. Many people with HIV/AIDS take these medications, and they may be at an increased risk of gaining weight due to their effects on metabolism.

Steroid injections

Intramuscular steroid injections are commonly used to treat inflammatory conditions, such as arthritis and back pain. These medications may also lead to weight gain in some individuals. This is one of the final and considered common medications that can lead to weight gain.

All in all, these are some medications that are believed to cause weight gain or increase the likelihood of gaining weight. If you are using any of these medications and have concerns about weight gain, talk to your doctor about possible alternatives or ways to manage the side effects.

With proper education and guidance, you can find a treatment plan that meets your needs and help you maintain a healthy body weight. And remember, medications should be used only after carefully weighing the risks and benefits of each option with your doctor.

How To Lose Weight From Medication Weight Gain?

How To Lose Weight From Medication Weight Gain?If you have gained weight due to medication, there are some things that can help you to lose some of the weight.

Discuss with Doctor

One of the first steps is to talk to your doctor about the issue. He/she may be able to switch you to a different medication that is not associated with weight gain or adjust your dosage in order to help reduce the amount of weight you’ve gained. This is the preferred option and should always be discussed with a doctor before any other steps are taken.

Make Dietary Changes

Even if you are on medications, making dietary changes can help you to lose some of the weight you have gained from the medications. Eating a balanced diet with plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats is important for maintaining a healthy weight. Also make sure to avoid processed foods, sugar-sweetened beverages, and other unhealthy food choices.

Regular Exercise

Regular physical activity can help you to lose weight and keep it off. Aim for at least 150 minutes of moderate-intensity exercise such as walking, swimming, jogging, or biking each week. Strength training is also important for maintaining muscle mass and bone density. If you are unsure about how to start an exercise plan, talk to a doctor or certified fitness professional who can help guide you in the right direction.

Monitor Progress

Regularly monitoring your progress can help you to stay on track and make adjustments as needed. Make sure to weigh yourself regularly and keep track of your diet and exercise habits so that you can identify areas where changes may be necessary. If possible, take measurements such as waist circumference or body fat percentage in addition to weighing yourself.

Seek Support

Lastly, don’t be afraid to seek support from family and friends. They can help encourage you during times when you feel like giving up or may provide helpful advice from their own experiences. Additionally, there are many online resources such as support groups and health forums that can be beneficial in your journey to losing weight from medication-related weight gain.

By following these steps and working with your doctor, you can take the necessary steps to lose weight from medication-related weight gain. Although it may be challenging at times, stay focused on your goals. And remember that any step in the right direction is better than no movement at all!


To conclude, medication weight gain is often an overlooked side effect of many prescription and over-the-counter medications. However, it can often have a significant impact on an individual’s health and well-being. It is important to be aware of potential weight gain before taking any medication and discuss this with your doctor if necessary.

Additionally, lifestyle modifications such as increasing physical activity levels. And consuming healthy diets can help to limit the potential for weight gain. Lastly, if you are already experiencing medication-related weight gain, it is important to talk to your doctor. And find ways of managing and possibly reversing the unwanted effects.

Seek the expertise of FitMantra for more information! Our experienced nutritionists can be easily accessed with just a few clicks. And will offer personalized support to assist you in achieving your fitness goals. Our online nutrition counseling, and weight loss program has been designed to help you shed those unwanted pounds! Don’t forget to download our Fitness App available on Android.

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